Contraindicated (1)pentobarbital will reduce the level or outcome of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is liable for the formation and elimination of cariprazine's Energetic metabolites.
pentobarbital will lessen the level or effect of repaglinide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the extent or impact of vincristine liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.
pentobarbital will lessen the extent or influence of phenytoin by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.
pentobarbital decreases levels of vandetanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay away from coadministration with strong CYP3A4 inducers; these drugs decrease publicity to vandetanib by around forty%.
Check Carefully (1)pentobarbital will lower the level or impact of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. For people acquiring exemestane with a powerful CYP3A4 inducer the encouraged dose of exemestane is fifty mg day-to-day after a meal.
With therapeutic doses of TCAs, barbiturates raise metabolism and decrease blood concentrations of TCAs.
pentobarbital will lower the extent or result of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will decrease the level or impact of ritonavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the extent or influence of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Potent or average CYP3A4 inducers may possibly increase level of diazepam elimination; thus, efficacy of diazepam could possibly be lowered.
pentobarbital will reduce the level or impact of terbinafine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or influence of fludrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the level or outcome of ketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
Withdrawal indications occur in infants born to mothers who acquire barbiturates throughout the last trimester of more info pregnancy